Program: Clinical Microscopy
Course Teacher: Mr. Delbert Robinson
Institution: Northern Carribbean University
Deadline: April 2, 2015
Group 1 Members':
Subject: Acute and Chronic Glomerulonephritis
Glomerulonephritis is a form of kidney disease in which the section of the kidneys that help filtering wastes and fluids from your blood is damage. Damage to the glomeruli causes blood and necessary protein to be shed in the urine. Glomerulonephritis can also be defined as a sterile, inflammatory condition affecting glomerulus, causing protein in blood and cast in the urine. When the glomerulus is affected the kidney probably would not function correctly hence, if the kidney is definitely not working properly a build-up of excessive salt and fluid can be in the body. This could lead to complications such as high blood pressure and in some cases kidney failure can happen. Glomerulonephritis is commonly due to a person while using body's immunity process works to protect the body against things like contamination caused by bacterias. Symptoms of glomerulonephritis typically develop between one (1) and three (3) week after the initial contamination. Other bacteria, viruses, parasites or fungi can bring about glomerulonephritis. Glomerulonephritis can lead to nephrotic syndrome. The primary syndrome would be that the kidneys leak a lot of protein as a result of damage to the glomeruli. This lead to proteinuria. Other symptoms may lead to tiredness and listlessness, a poor urge for food and diarrhoea or nausea. Glomerulonephritis may be acute or chronic. Severe glomerulonephritis may come about because of an infection just like strep neck, chickenpox or perhaps malaria. Within an acute circumstance of glomerulonephritis, the antibodies that are developed to get rid of the human body's infection continue to attack the glomeruli while on the furthermore with long-term glomerulonephritis, doctors sometimes are not able to pinpoint the particular cause. Strategy, chronic glomerulonephritis can be the product of a hereditary disorder or perhaps an autoimmune disorder such as lupus in which the body's immune system episodes various systems in the body. A few common regarding this type of disease include; lilac or weakling urine. Additional symptoms consist of, vomiting, sleepiness, appetite dropped, decrease urination, itchy skin area and sometimes fever. Symptoms may last for couple of weeks or a lot of days. Regarding diagnosis the doctor make the prognosis from the health background and urine test that shows necessary protein and blood cells. Ultrasound and biopsy is required to make the definitive medical diagnosis and to better decide the correct treatment process for a person suffering from this disease. In children recovery is much faster. Sometimes glomerulonephritis goes away on its own, however , at times medication that affect the immune system like steroid have been utilized. A special treatment call plasmaphersis is sometimes necessary. In this method blood is definitely filtered to take out antibodies in it and it is replaced with intravenous fluid or perhaps donated sang. There is no certain treatment of this chronic form of disease; but following a specific diet that may be low in healthy proteins, salt and potassium is vital. Pathogenesis
Often , the precise cause by particular problems with your body's immune system, causing immunologic disorders throughout the body, including the body system. Firstly; immune system complexes will be formed, this can be as a result of the immunologic reactions. Secondly; this kind of increase the serum immunoglobulins. Finally; these are in that case circulated inside the bloodstream and fourth; they then deposited for the glomerular membrane. Signs/ Symptoms
The most common symptoms includes:
1 ) Hematuria (dark, brown or perhaps rusty coloured)
2 . Proteinuria
3. Foamy urine
5. Swelling of the face, eye, ankle, feet, legs and abdomen. Symptoms which...
References: 1 . Beckett, G., Master, S., Rae, P., & Ashby, G. (n. g. ). Scientific Biochemistry 7th edition. Blackwell P.
2 . Brunzel, In. A. (1994). Fundamentals of Urine and Body Fluidd Analysis second edition. Chinese suppliers: Saunders.
a few. Strasinger, H. K., & Lorenzo, Meters. S. (2008). Urialysis and Body Fluids 5th copy. Philadephia: Electronic. A. Davis Company.